The Gilles de la Tourette Syndrome-Quality of Life Scale for children and adolescents (C&A-GTS-QOL):development and validation of the Italian version


Autoria(s): Cavanna, Andrea E.; Luoni, Chiara; Blangiardo, Rosanna; Eddy, Clare M.; Silvestri, Paola R.; Calì, Paola V.; Seri, Stefano; Balottin, Umberto; Cardona, Francesco; Rizzo, Renata; Termine, Cristiano
Data(s)

06/05/2013

Resumo

BACKGROUND: Gilles de la Tourette syndrome (GTS) is a chronic childhood-onset neuropsychiatric disorder with a significant impact on patients' health-related quality of life (HR-QOL). Cavanna et al. (Neurology 2008; 71: 1410-1416) developed and validated the first disease-specific HR-QOL assessment tool for adults with GTS (Gilles de la Tourette Syndrome-Quality of Life Scale, GTS-QOL). This paper presents the translation, adaptation and validation of the GTS-QOL for young Italian patients with GTS. METHODS: A three-stage process involving 75 patients with GTS recruited through three Departments of Child and Adolescent Neuropsychiatry in Italy led to the development of a 27-item instrument (Gilles de la Tourette Syndrome-Quality of Life Scale in children and adolescents, C&A-GTS-QOL) for the assessment of HR-QOL through a clinician-rated interview for 6-12 year-olds and a self-report questionnaire for 13-18 year-olds. RESULTS: The C&A-GTS-QOL demonstrated satisfactory scaling assumptions and acceptability. Internal consistency reliability was high (Cronbach's alpha > 0.7) and validity was supported by interscale correlations (range 0.4-0.7), principal-component factor analysis and correlations with other rating scales and clinical variables. CONCLUSIONS: The present version of the C&A-GTS-QOL is the first disease-specific HR-QOL tool for Italian young patients with GTS, satisfying criteria for acceptability, reliability and validity. © 2013 - IOS Press and the authors. All rights reserved.

Formato

application/pdf

Identificador

http://eprints.aston.ac.uk/18389/1/Gilles_de_la_Tourette_Syndrome_Quality_of_Life_Scale_for_children_and_adolescents.pdf

Cavanna, Andrea E.; Luoni, Chiara; Blangiardo, Rosanna; Eddy, Clare M.; Silvestri, Paola R.; Calì, Paola V.; Seri, Stefano; Balottin, Umberto; Cardona, Francesco; Rizzo, Renata and Termine, Cristiano (2013). The Gilles de la Tourette Syndrome-Quality of Life Scale for children and adolescents (C&A-GTS-QOL):development and validation of the Italian version. Behavioural Neurology, 27 (1), pp. 95-103.

Relação

http://eprints.aston.ac.uk/18389/

Tipo

Article

PeerReviewed