Thiosemicarbazones active against Clostridium difficile
| Data(s) |
01/03/2008
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| Resumo |
A set of closely related furylidene thiosemicarbazones was prepared and screened against various clinically important Gram-positive bacteria. One compound containing an ethylene spacer and a 5-nitrofuryl group was found to have promising activity against Clostridium difficile. |
| Formato |
application/pdf |
| Identificador |
http://eprints.aston.ac.uk/4911/1/BMCL_2008_17081711.pdf Costello, Cait; Karpanen, Tarja; Lambert, Peter A.; Mistry, Preena; Parker, Katy J.; Rathbone, Daniel L.; Ren, Jiangmeng; Wheeldon, Laura and Worthington, Tony (2008). Thiosemicarbazones active against Clostridium difficile. Bioorganic and Medicinal Chemistry Letters, 18 (5), pp. 1708-1711. |
| Relação |
http://eprints.aston.ac.uk/4911/ |
| Tipo |
Article PeerReviewed |
