Synthesis of 'difficult' peptides free of aspartimide and related products, using peptoid methodology
| Data(s) |
01/01/2006
|
|---|---|
| Resumo |
We developed an efficient, cost effective strategy for Fmoc-based solid phase synthesis of 'difficult' peptides and/or peptides containing Asp/Asn-Gly sequences, free of aspartimide and related products, using a peptoid methodology for the preparation of N-substituted glycines. |
| Identificador | |
| Idioma(s) |
eng |
| Publicador |
Pergamon |
| Palavras-Chave | #Aspartimide #Backbone Protection #Caged Peptides #'difficult' #Peptides #Peptoid #Chemistry, Organic #Solid-phase Synthesis #Backbone-amide Protection #Fmoc-based Spps #2-hydroxy-4-methoxybenzyl #Strategies #Blocks #Linker #Acids #C1 |
| Tipo |
Journal Article |
