The acidic nature of the CcmG redox-active center is important for cytochrome c maturation in Escherichia coli
Data(s) |
01/06/2004
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Resumo |
Cytochrome c biogenesis in Escherichia coli is a complex process requiring at least eight genes (ccmABC DEFGH). One of these genes, ccmG, encodes a thioredoxin-like protein with unusually specific redox activity. Here, we investigate the basis for CcmG function and demonstrate the importance of acidic residues surrounding the redox-active center. |
Identificador |
http://espace.library.uq.edu.au/view/UQ:73865/UQ73865_OA.pdf |
Idioma(s) |
eng |
Publicador |
American Society for Microbiology |
Palavras-Chave | #Microbiology #Thioredoxin-like Protein #Mixed Disulfide Intermediate #Crystal-structure #In-vivo #Periplasmic Thioredoxin #Electron-transfer #Bond Formation #Heme-binding #Biogenesis #Membrane |
Tipo |
Journal Article |