Reactions catalyzed by bacterial cytochromes P450


Autoria(s): Cryle, M. J.; Stok, J. E.; De Voss, J. J.
Data(s)

01/01/2003

Resumo

The cytochromes P450 are a large family of oxidative haemoproteins that are responsible for a wide variety of oxidative transformations in a variety of organisms. This review focuses upon the reactions catalyzed specifically by bacterial enzymes, which includes aliphatic hydroxylation, alkene epoxidation, aromatic hydroxylation, oxidative phenolic coupling, heteroatom oxidation and dealkylation, and multiple oxidations including C-C bond cleavage. The potential for the practical application of the oxidizing power of these enzymes is briefly discussed.

Identificador

http://espace.library.uq.edu.au/view/UQ:66208

Idioma(s)

eng

Publicador

CSIRO Publishing

Palavras-Chave #Chemistry, Multidisciplinary #Biosynthetic Gene-cluster #Polycyclic Aromatic-hydrocarbons #Mycobacterium-aurum Mo1 #Herbicide-inducible Cytochromes-p-450 #Nucleoside Antibiotic Nikkomycin #Tissue-selective Inhibitor #Site-specific Mutagenesis #Sp Strain He5 #Streptomyces-venezuelae #Sterol 14-alpha-demethylase #C1 #270108 Enzymes #780103 Chemical sciences
Tipo

Journal Article