Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant


Autoria(s): Earnshaw, W. C.; Allshire, R. C.; Black, B. E.; Bloom, K.; Brinkley, B. R.; Brown, W.; Cheeseman, I. M.; Choo, K. H. A.; Copenhaver, G. P.; DeLuca, J. G.; Desai, A.; Diekmann, S.; Erhardt, S.; Fitzgerald-Hayes, M.; Foltz, D.; Fukagawa, T.; Gassmann, R.; Gerlich, D. W.; Glover, D. M.; Gorbsky, G. J.; Harrison, S. C.; Heun, P.; Hirota, T.; Jansen, L. E. T.; Karpen, G.; Kops, G. J. P. L.; Lampson, M. A.; Lens, S. M.; Losada, A.; Luger, K.; Maiato, H.; Maddox, P. S.; Margolis, R. L.; Masumoto, H.; McAinsh, A. D.; Mellone, B. G.; Meraldi, P.; Musacchio, A.; Oegema, K.; O’Neill, R. J.; Salmon, E. D.; Scott, K. C.; Straight, A. F.; Stukenberg, P. T.; Sullivan, B. A.; Sullivan, K. F.; Sunkel, C. E.; Swedlow, J. R.; Walczak, C. E.; Warburton, P. E.; Westermann, S.; Willard, H. F.; Wordeman, L.; Yanagida, M.; Yen, T. J.; Yoda, K.; Cleveland, D. W.
Data(s)

24/05/2016

24/05/2016

12/04/2013

Resumo

The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this protein CenH3. Here, we argue that the original name should be maintained both because it is the basis of a long established nomenclature for centromere proteins and because it avoids confusion due to the presence of canonical histone H3 at centromeres.

Wellcome Trust grants: (073915, 095021, 077707, 092076); NIH grants : (R01-GM082989, R37 GM32238, GM074150, GM088313, R01GM088371, R01-50412, 5R01GM61169, GM083988, R01GM088716, R37GM024364, R01GM074728, R01 GM063045, R01 GM098500, GM059618, GM69429, GM083988, ); Burroughs Wellcome Fund; Rita Allen Foundation Scholar Award; Ludwig Institute; National Science Foundation grant: (MCB-1121563); Government of Japan (Funding Program for Next Generation World-Leading Researchers); EMBO Installation Grant; Cancer Research UK; NIGMS; Oklahoma Center for Advancement of Science and Technology; McCasland Foundation; Japanese Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology in Japan; FCT grants: (BIA-BCM/100557/2008, BIAPRO/100537/2008, PTDC/SAU-GMG/099704/2008, PTDC/SAU-ONC/112917/2009); ERC (KINSIGN); Netherlands Organisation for Scientific Research grants: (NWO-Vici-016.130.661, NWO-Vici-91812610); Dutch Cancer Society grants: (UU2009-4311, UU2011-5134); Spanish Ministry of Economy grants: (CSD2007-015, SAF2010-25157); European Research Council - 7th framework program and Human Frontier Science Program grant: (PRECISE); BBSRC grants: (BB/I021353/1, BB/H013024); Kazusa DNA Research Institute Foundation; CCSRI grant: (700824); NSF award number: (1024973); Swiss National Foundation; University of Geneva; Foundation Louis-Jeantet; March of Dimes grant: (6-FY10-294); COMPETE and ON2; Science Foundation Ireland grant: (12/IA/1370); Core Grant: (CA06927); Commonwealth of Pennsylvania.

Identificador

Earnshaw, W. C., Allshire, R. C., Black, B. E., Bloom, K., Brinkley, B. R., Brown, W., Cheeseman, I. M., Choo, K. H. A., Copenhaver, G. P., Deluca, J. G., Desai, A., Diekmann, S., Erhardt, S., Fitzgerald-Hayes, M., Foltz, D., Fukagawa, T., Gassmann, R., Gerlich, D. W., Glover, D. M., Gorbsky, G. J., Harrison, S. C., Heun, P., Hirota, T., Jansen, L. E. T., Karpen, G., Kops, G. J. P. L., Lampson, M. A., Lens, S. M., Losada, A., Luger, K., Maiato, H., Maddox, P. S., Margolis, R. L., Masumoto, H., McAinsh, A. D., Mellone, B. G., Meraldi, P., Musacchio, A., Oegema, K., O’Neill, R. J., Salmon, E. D., Scott, K. C., Straight, A. F., Stukenberg, P. T., Sullivan, B. A., Sullivan, K. F., Sunkel, C. E., Swedlow, J. R., Walczak, C. E., Warburton, P. E., Westermann, S., Willard, H. F., Wordeman, L., Yanagida, M., Yen, T. J., Yoda, K., Cleveland, D. W. (2013). Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res., 21(2), 101–106.

http://hdl.handle.net/10400.7/619

10.1007/s10577-013-9347-y

Idioma(s)

eng

Publicador

Springer Verlag

Relação

info:eu-repo/grantAgreement/EC/FP7/241548/EU

info:eu-repo/grantAgreement/EC/FP7/258068/EU

info:eu-repo/grantAgreement/EC/FP7/281198/EU

info:eu-repo/grantAgreement/EC/FP7/311674/EU

info:eu-repo/grantAgreement/EC/FP7/238176/EU

precise

http://link.springer.com/article/10.1007%2Fs10577-013-9347-y

Direitos

openAccess

http://creativecommons.org/licenses/by/4.0/

Palavras-Chave #Autoantigens #Centromere #Chromosomal Proteins, Non-Histone #Histones #Humans #Kinetochores #Scleroderma, Systemic #Terminology as Topic
Tipo

article