2-Aminobenzimidazole Organocatalyzed Asymmetric Amination of Cyclic 1,3-Dicarbonyl Compounds
| Contribuinte(s) |
Universidad de Alicante. Departamento de Química Orgánica Universidad de Alicante. Instituto Universitario de Síntesis Orgánica Catálisis Estereoselectiva en Síntesis Orgánica (CESO) Síntesis Asimétrica (SINTAS) Nuevos Materiales y Catalizadores (MATCAT) |
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| Data(s) |
08/02/2016
08/02/2016
2015
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| Resumo |
The use of a trans-cyclohexanediamine benzimidazole derivative as a hydrogen-bond catalyst for the electrophilic amination of cyclic 1,3-dicarbonyl compounds is herein presented. High yields and enantioselectivities varying from moderate to excellent are generally obtained using mild reaction conditions and as low as 1 mol% of catalyst loading. Financial support from the University of Alicante (VIGROB-173, GRE12-03, UAUSTI13-01, UAUSTI13-02) is gratefully acknowledged. |
| Identificador |
Synlett. 2015, 26(01): 95-100. doi:10.1055/s-0034-1379494 0936-5214 (Print) 1437-2096 (Online) http://hdl.handle.net/10045/52886 10.1055/s-0034-1379494 |
| Idioma(s) |
eng |
| Publicador |
Georg Thieme Verlag |
| Relação |
http://dx.doi.org/10.1055/s-0034-1379494 |
| Direitos |
© Georg Thieme Verlag Stuttgart · New York info:eu-repo/semantics/openAccess |
| Palavras-Chave | #Organocatalysis #Electrophilic amination #Asymmetric catalysis #Dicarbonyl compounds #Benzimidazole #Química Orgánica |
| Tipo |
info:eu-repo/semantics/article |
