Osmium Catalyst for the Borrowing Hydrogen Methodology: α-Alkylation of Arylacetonitriles and Methyl Ketones
| Contribuinte(s) |
Universidad de Alicante. Departamento de Química Orgánica Universidad de Alicante. Instituto Universitario de Síntesis Orgánica Nuevos Materiales y Catalizadores (MATCAT) Síntesis Asimétrica (SINTAS) |
|---|---|
| Data(s) |
12/09/2014
12/09/2014
29/07/2013
|
| Resumo |
Complex [Os(η6-p-cymene)(OH)(IPr)]OTf is an efficient catalyst precursor for the α-alkylation of arylacetonitriles and methyl ketones with alcohols, which works with turnover frequencies between 675 and 176 h–1 for nitriles and between 194 and 28 h–1 for ketones. Financial support from the Spanish MINECO [Projects CTQ2007-65218/BQU, CTQ2011-23459, CTQ2011-24165, and Consolider Ingenio 2010 (CSD2007-00006)], the DGA (E35), Generalitat Valenciana (PROMETEO/2009/039 and FEDER), and the European Social Fund (FSE) is acknowledged. |
| Identificador |
ACS Catalysis. 2013, 3(9): 2072-2075. doi:10.1021/cs4005375 2155-5435 http://hdl.handle.net/10045/40225 10.1021/cs4005375 |
| Idioma(s) |
eng |
| Publicador |
American Chemical Society |
| Relação |
http://dx.doi.org/10.1021/cs4005375 |
| Direitos |
© 2013 American Chemical Society info:eu-repo/semantics/restrictedAccess |
| Palavras-Chave | #Osmium #Borrowing hydrogen #Hydrogen autotransfer #Nitriles alkylation #Ketones alkylation #Química Orgánica |
| Tipo |
info:eu-repo/semantics/article |
