Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes
| Contribuinte(s) |
Universidad de Alicante. Departamento de Química Orgánica Universidad de Alicante. Instituto Universitario de Síntesis Orgánica Síntesis Asimétrica (SINTAS) |
|---|---|
| Data(s) |
05/06/2014
05/06/2014
2014
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| Resumo |
This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective strategies is described remarking the scope and main features of each one. This work has been supported by the Spanish Ministerio de Economía y Competitividad (MINECO) (Consolider INGENIO 2010 CSD2007-00006, CTQ2010-20387), FEDER, Generalitat Valenciana (PROMETEO/2009/039), and by the University of Alicante. |
| Identificador |
Current Topics in Medicinal Chemistry. 2014, 14(10): 1271-1282. doi:10.2174/1568026614666140423112145 1568-0266 (Print) 1873-5294 (Online) http://hdl.handle.net/10045/37876 10.2174/1568026614666140423112145 |
| Idioma(s) |
eng |
| Publicador |
Bentham Science Publishers |
| Relação |
http://dx.doi.org/10.2174/1568026614666140423112145 |
| Direitos |
© 2014 Bentham Science Publishers info:eu-repo/semantics/openAccess |
| Palavras-Chave | #Antitumoral #Asymmetric synthesis #Catalysis #Cycloaddition #Metal #Organocatalyst #Química Orgánica |
| Tipo |
info:eu-repo/semantics/article |
