Phosphonate and quinoxaline cavitands for molecular recognition and sensing


Autoria(s): Barboza, Tahnie
Data(s)

18/03/2016

Resumo

In the last decade, phosphonate and quinoxaline cavitand have been extensively studied, highlighting their outstanding recognition properties. Their successful applications in material science and sensing open the way to new potential applications, such as border security, environmental monitoring and chiral recognition. The present thesis explores the recognition properties of phosphonate and quinoxaline cavitands towards new targets, for molecular recognition and sensing applications. Chapter 2 highlights the enantioselective behavior of phosphonate cavitands towards chiral guests in the solid state and in solution. Phosphonate cavitands were exploited for the molecular recognition of L-lactic acid (chapter 3), a widespread natural molecule which offer multiple potential applications, and a human sweat marker used for the detection of human presence (chapter 4). The second part is devoted to sensing applications of quinoxaline cavitands. Chapter 5 describes the use of QxCav for the preconcentration of drugs precursors, while chapter 6 reports the design, synthesis and grafting of a rigidified EtQxBox on a silicon wafer.

Identificador

http://hdl.handle.net/1889/3082

Idioma(s)

Inglese

Publicador

Università degli Studi di Parma. Dipartimento di Chimica

Relação

Dottorato di ricerca in Scienza e Tecnologia dei Materiali Innovativi

Palavras-Chave #Phosphonate cavitand #Quinoxaline cavitand #Sensing #Molecular recognition #Inherent chirality #Chiral recognition #Lactic acid #3H3MHA #Drugs precursors #Non compilare #CHIM/04
Tipo

Doctoral thesis