Neuronal human BACE1 knock-in induces systemic diabetes in mice
| Data(s) |
30/05/2016
30/05/2016
01/07/2016
|
|---|---|
| Resumo |
Funding We would like to thank R. Simcox, Romex Oilfield Chemicals, for financial support for KP, and acknowledge additional contributions from the Scottish Alzheimer’s Research UK network for the lipidomics work. The College of Life Science and Medicine, University of Aberdeen, sponsored the imaging study. MD was funded by British Heart Foundation and Diabetes UK; NM was funded by a British Heart Foundation Intermediate Fellowship; KS was funded by a European Foundation for the Study of Diabetes/Lilly programme grant; and RD was funded by an Institute of Medical Sciences PhD studentship. Peer reviewed Publisher PDF |
| Formato |
11 |
| Identificador |
Plucińska , K , Dekeryte , R , Koss , D , Shearer , K , Mody , N , Whitfield , P D , Doherty , M K , Mingarelli , M , Welch , A , Riedel , G , Delibegovic , M & Platt , B 2016 , ' Neuronal human BACE1 knock-in induces systemic diabetes in mice ' Diabetologia , vol 59 , no. 7 , pp. 1513-1523 . , 10.1007/s00125-016-3960-1 0012-186X PURE: 63896262 PURE UUID: 075ba402-0785-4123-bcc8-81afc56f3750 PubMed: 27138913 |
| Idioma(s) |
eng |
| Relação |
Diabetologia |
| Direitos |
© The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| Palavras-Chave | #neuronal BACE1 #glucose homeostasis #ceramide #ER stress #18FDG-PET #insulin signalling #R Medicine #British Heart Foundation #R |
| Tipo |
Journal article |
| Contribuinte(s) |
University of Aberdeen, School of Medical Sciences University of Aberdeen, University of Aberdeen University of Aberdeen, Medicine, Medical Sciences & Nutrition, Medical Sciences University of Aberdeen, Medicine, Medical Sciences & Nutrition, Other Applied Health Sciences University of Aberdeen, Medical Sciences - Cardiovascular Group University of Aberdeen, Medicine, Medical Sciences & Nutrition, Applied Medicine |
