Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment


Autoria(s): Sintusek, Palittiya; Catapano, Francesco; Angkathunkayul, Napat; Marrosu, Elena; Parson, Simon H; Morgan, Jennifer E; Muntoni, Francesco; Zhou, Haiyan
Data(s)

13/05/2016

13/05/2016

10/05/2016

Resumo

Funding: This study is supported by the National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust and University College London (FM and HZ), the Medical Research Council grant (grant reference MR/L013142/1, FM), SMA-Europe grant (FM and HZ) and Great Ormond Street Hospital Children’s Charity grants (FM and JM). JEM is supported by Great Ormond Street Hospital Children’s Charity. PS is supported by Bill Marshall Fellowship and The CP Charitable Trust at Great Ormond Street Hospital and UCL. SHP is supported by SMA Trust and Euan MacDonald Centre for Motor Neurone Disease Research.

Peer reviewed

Publisher PDF

Identificador

Sintusek , P , Catapano , F , Angkathunkayul , N , Marrosu , E , Parson , S H , Morgan , J E , Muntoni , F & Zhou , H 2016 , ' Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment ' PLoS ONE , vol 11 , no. 5 , 0155032 . , 10.1371/journal.pone.0155032

1932-6203

PURE: 66129627

PURE UUID: f4c1bfbe-5e54-496b-b741-7d565c198a52

PubMed: 27163330

http://hdl.handle.net/2164/5986

http://dx.doi.org/10.1371/journal.pone.0155032

Idioma(s)

eng

Relação

PLoS ONE

Direitos

Copyright: © 2016 Sintusek et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. http://creativecommons.org/licenses/by/4.0/

Palavras-Chave #R Medicine #Medical Research Council (MRC) #MR/L013142/1 #R
Tipo

Journal article

Contribuinte(s)

University of Aberdeen, Medicine, Medical Sciences & Nutrition, Medical Education