Magnetoencephalography as a putative biomarker for Alzheimer's disease.


Autoria(s): Zamrini, Edward; Pekkonen, Eero; Maestú, Fernando; Funke, Michael; Makela, Jyrki; Myles, Riley; Bajo Breton, Ricardo; Sudre, Gustavo; Fernández, Alberto; Perales Castellanos, Nazareth; Pozo Guerrero, Francisco del; Stam, C.J.; Van Dijk, Bob W.; Bagic, Anto; Becker, James T.
Data(s)

01/04/2011

Resumo

Alzheimer’s Disease (AD) is the most common dementia in the elderly and is estimated to affect tens of millions of people worldwide. AD is believed to have a prodromal stage lasting ten or more years. While amyloid deposits, tau filaments, and loss of brain cells are characteristics of the disease, the loss of dendritic spines and of synapses predate such changes. Popular preclinical detection strategies mainly involve cerebrospinal fluid biomarkers, magnetic resonance imaging, metabolic PET scans, and amyloid imaging. One strategy missing from this list involves neurophysiological measures, which might be more sensitive to detect alterations in brain function. The Magnetoencephalography International Consortium of Alzheimer’s Disease arose out of the need to advance the use of Magnetoencephalography (MEG), as a tool in AD and pre-AD research. This paper presents a framework for using MEG in dementia research, and for short-term research priorities

Formato

application/pdf

Identificador

http://oa.upm.es/12146/

Idioma(s)

eng

Publicador

E.T.S.I. Telecomunicación (UPM)

Relação

http://oa.upm.es/12146/1/INVE_MEM_2011_109405.pdf

http://www.hindawi.com/journals/ijad/2011/280289/

info:eu-repo/semantics/altIdentifier/doi/10.4061/2011/280289

Direitos

http://creativecommons.org/licenses/by-nc-nd/3.0/es/

info:eu-repo/semantics/openAccess

Fonte

International Journal of Alzheimer's Disease, ISSN 2090-0252, 2011-04, No. 2011

Palavras-Chave #Telecomunicaciones
Tipo

info:eu-repo/semantics/article

Artículo

PeerReviewed