Directional DBS improves therapeutic window: from model prediction to human use


Autoria(s): Pollo, Claudio; Kaelin, Alain; Oertel, Markus Florian; Stieglitz, Lennart; Rossi-Mossuti, Frédéric Gianfranco Gualtiero; Lozano, A; Raabe, Andreas; Schüpbach, Michael
Data(s)

2015

Resumo

Deep brain stimulation of different targets has been shown to drastically improve symptoms of a variety of neurological conditions. However, the occurrence of disabling side effects may limit the ability to deliver adequate amounts of current necessary to reach the maximal benefit. Computed models have suggested that reduction in electrode size and the ability to provide directional stimulation could increase the efficacy of such therapies. This has never been demonstrated in humans. In the present study, we assess the effect of directional stimulation compared to omnidirectional stimulation.

Formato

application/pdf

Identificador

http://boris.unibe.ch/81174/1/pdf.pdf

Pollo, Claudio; Kaelin, Alain; Oertel, Markus Florian; Stieglitz, Lennart; Rossi-Mossuti, Frédéric Gianfranco Gualtiero; Lozano, A; Raabe, Andreas; Schüpbach, Michael (2015). Directional DBS improves therapeutic window: from model prediction to human use. Brain stimulation, 8(2), pp. 380-381. Elsevier 10.1016/j.brs.2015.01.218 <http://dx.doi.org/10.1016/j.brs.2015.01.218>

doi:10.7892/boris.81174

info:doi:10.1016/j.brs.2015.01.218

urn:issn:1935-861X

Idioma(s)

eng

Publicador

Elsevier

Relação

http://boris.unibe.ch/81174/

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Pollo, Claudio; Kaelin, Alain; Oertel, Markus Florian; Stieglitz, Lennart; Rossi-Mossuti, Frédéric Gianfranco Gualtiero; Lozano, A; Raabe, Andreas; Schüpbach, Michael (2015). Directional DBS improves therapeutic window: from model prediction to human use. Brain stimulation, 8(2), pp. 380-381. Elsevier 10.1016/j.brs.2015.01.218 <http://dx.doi.org/10.1016/j.brs.2015.01.218>

Palavras-Chave #610 Medicine & health
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed