Combination therapy for multidrug-resistant cytomegalovirus disease
| Data(s) |
01/10/2015
|
|---|---|
| Resumo |
Multidrug-resistant (MDR) cytomegalovirus (CMV) emerged after transient responses to ganciclovir, foscarnet, and cidofovir in a CMV-seropositive recipient who underwent allogeneic hematopoietic stem cell transplantation from a CMV-seronegative donor. Experimental treatments using leflunomide and artesunate failed. Re-transplantation from a CMV-seropositive donor supported by adoptive transfer of pp65-specific T cells and maribavir was followed by lasting suppression. This case illustrates that successful MDR CMV therapy may require individualized multidisciplinary approaches. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/78706/1/AR_tid12435.pdf Stuehler, C.; Stüssi, G.; Halter, J.; Nowakowska, J.; Schibli, A.; Battegay, M.; Dirks, J.; Passweg, J.; Heim, D.; Rovó, Alicia; Kalberer, C.; Bucher, C.; Weisser, M.; Dumoulin, A.; Hirsch, H.H.; Khanna, N. (2015). Combination therapy for multidrug-resistant cytomegalovirus disease. Transplant infectious disease, 17(5), pp. 751-755. Wiley 10.1111/tid.12435 <http://dx.doi.org/10.1111/tid.12435> doi:10.7892/boris.78706 info:doi:10.1111/tid.12435 info:pmid:26432076 urn:issn:1398-2273 |
| Idioma(s) |
eng |
| Publicador |
Wiley |
| Relação |
http://boris.unibe.ch/78706/ |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Stuehler, C.; Stüssi, G.; Halter, J.; Nowakowska, J.; Schibli, A.; Battegay, M.; Dirks, J.; Passweg, J.; Heim, D.; Rovó, Alicia; Kalberer, C.; Bucher, C.; Weisser, M.; Dumoulin, A.; Hirsch, H.H.; Khanna, N. (2015). Combination therapy for multidrug-resistant cytomegalovirus disease. Transplant infectious disease, 17(5), pp. 751-755. Wiley 10.1111/tid.12435 <http://dx.doi.org/10.1111/tid.12435> |
| Palavras-Chave | #610 Medicine & health |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
