The new macrolide-lincosamide-streptogramin B resistance gene erm(45) is located within a genomic island in Staphylococcus fleurettii.


Autoria(s): Wipf, Juliette Ramona Karin; Schwendener, Sybille; Nielsen, Jesper Boye; Westh, Henrik; Perreten, Vincent
Data(s)

01/06/2015

Resumo

Genome alignment of a macrolide, lincosamide, and streptogramin B (MLSB)-resistant Staphylococcus fleurettii strain with an MLSB-susceptible S. fleurettii strain revealed a novel 11,513-bp genomic island carrying the new erythromycin resistance methylase gene erm(45). This gene was shown to confer inducible MLSB resistance when cloned into Staphylococcus aureus. The erm(45)-containing island was integrated into the housekeeping gene guaA in S. fleurettii and was able to form a circular intermediate but was not transmissible to S. aureus.

Formato

application/pdf

Identificador

http://boris.unibe.ch/77118/1/Antimicrob.%20Agents%20Chemother.-2015-Wipf-3578-81.pdf

Wipf, Juliette Ramona Karin; Schwendener, Sybille; Nielsen, Jesper Boye; Westh, Henrik; Perreten, Vincent (2015). The new macrolide-lincosamide-streptogramin B resistance gene erm(45) is located within a genomic island in Staphylococcus fleurettii. Antimicrobial agents and chemotherapy, 59(6), pp. 3578-3581. American Society for Microbiology 10.1128/AAC.00369-15 <http://dx.doi.org/10.1128/AAC.00369-15>

doi:10.7892/boris.77118

info:doi:10.1128/AAC.00369-15

info:pmid:25779586

urn:issn:0066-4804

Idioma(s)

eng

Publicador

American Society for Microbiology

Relação

http://boris.unibe.ch/77118/

Direitos

info:eu-repo/semantics/openAccess

Fonte

Wipf, Juliette Ramona Karin; Schwendener, Sybille; Nielsen, Jesper Boye; Westh, Henrik; Perreten, Vincent (2015). The new macrolide-lincosamide-streptogramin B resistance gene erm(45) is located within a genomic island in Staphylococcus fleurettii. Antimicrobial agents and chemotherapy, 59(6), pp. 3578-3581. American Society for Microbiology 10.1128/AAC.00369-15 <http://dx.doi.org/10.1128/AAC.00369-15>

Palavras-Chave #570 Life sciences; biology #630 Agriculture
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed