A Call for Systematic Research on Solute Carriers
| Data(s) |
30/07/2015
|
|---|---|
| Resumo |
Solute carrier (SLC) membrane transport proteins control essential physiological functions, including nutrient uptake, ion transport, and waste removal. SLCs interact with several important drugs, and a quarter of the more than 400 SLC genes are associated with human diseases. Yet, compared to other gene families of similar stature, SLCs are relatively understudied. The time is right for a systematic attack on SLC structure, specificity, and function, taking into account kinship and expression, as well as the dependencies that arise from the common metabolic space. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/75713/1/1-s2.0-S0092867415008995-main.pdf César-Razquin, Adrián; Snijder, Berend; Frappier-Brinton, Tristan; Isserlin, Ruth; Gyimesi, Gergely; Bai, Xiaoyun; Reithmeier, Reinhart A; Hepworth, David; Edwards, Aled M; Superti-Furga, Giulio; Hediger, Matthias (2015). A Call for Systematic Research on Solute Carriers. Cell, 162(3), pp. 478-487. Cell Press 10.1016/j.cell.2015.07.022 <http://dx.doi.org/10.1016/j.cell.2015.07.022> doi:10.7892/boris.75713 info:doi:10.1016/j.cell.2015.07.022 info:pmid:26232220 urn:issn:0092-8674 |
| Idioma(s) |
eng |
| Publicador |
Cell Press |
| Relação |
http://boris.unibe.ch/75713/ |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
César-Razquin, Adrián; Snijder, Berend; Frappier-Brinton, Tristan; Isserlin, Ruth; Gyimesi, Gergely; Bai, Xiaoyun; Reithmeier, Reinhart A; Hepworth, David; Edwards, Aled M; Superti-Furga, Giulio; Hediger, Matthias (2015). A Call for Systematic Research on Solute Carriers. Cell, 162(3), pp. 478-487. Cell Press 10.1016/j.cell.2015.07.022 <http://dx.doi.org/10.1016/j.cell.2015.07.022> |
| Palavras-Chave | #570 Life sciences; biology #610 Medicine & health |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
