Get real in individual participant data (IPD) meta-analysis: a review of the methodology.


Autoria(s): Debray, Thomas P A; Moons, Karel G M; van Valkenhoef, Gert; Efthimiou, Orestis; Hummel, Noemi; Groenwold, Rolf H H; Reitsma, Johannes B
Data(s)

19/08/2015

Resumo

Individual participant data (IPD) meta-analysis is an increasingly used approach for synthesizing and investigating treatment effect estimates. Over the past few years, numerous methods for conducting an IPD meta-analysis (IPD-MA) have been proposed, often making different assumptions and modeling choices while addressing a similar research question. We conducted a literature review to provide an overview of methods for performing an IPD-MA using evidence from clinical trials or non-randomized studies when investigating treatment efficacy. With this review, we aim to assist researchers in choosing the appropriate methods and provide recommendations on their implementation when planning and conducting an IPD-MA. © 2015 The Authors. Research Synthesis Methods published by John Wiley & Sons, Ltd.

Formato

application/pdf

application/pdf

Identificador

http://boris.unibe.ch/74622/1/Debray%20ResSynthMethods%202015.pdf

http://boris.unibe.ch/74622/2/Debray%20ResSynthMethods%202015_supplmat.pdf

Debray, Thomas P A; Moons, Karel G M; van Valkenhoef, Gert; Efthimiou, Orestis; Hummel, Noemi; Groenwold, Rolf H H; Reitsma, Johannes B (2015). Get real in individual participant data (IPD) meta-analysis: a review of the methodology. Research Synthesis Methods, 6(4), pp. 293-309. Wiley 10.1002/jrsm.1160 <http://dx.doi.org/10.1002/jrsm.1160>

doi:10.7892/boris.74622

info:doi:10.1002/jrsm.1160

info:pmid:26287812

urn:issn:1759-2879

Idioma(s)

eng

Publicador

Wiley

Relação

http://boris.unibe.ch/74622/

Direitos

info:eu-repo/semantics/openAccess

info:eu-repo/semantics/openAccess

Fonte

Debray, Thomas P A; Moons, Karel G M; van Valkenhoef, Gert; Efthimiou, Orestis; Hummel, Noemi; Groenwold, Rolf H H; Reitsma, Johannes B (2015). Get real in individual participant data (IPD) meta-analysis: a review of the methodology. Research Synthesis Methods, 6(4), pp. 293-309. Wiley 10.1002/jrsm.1160 <http://dx.doi.org/10.1002/jrsm.1160>

Palavras-Chave #610 Medicine & health #360 Social problems & social services
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed