Basophils exhibit antibacterial activity through extracellular trap formation.


Autoria(s): Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe
Data(s)

01/09/2015

Resumo

Basophils are primarily associated with immunomodulatory functions in allergic diseases and parasitic infections. Recently, it has been demonstrated that both activated human and mouse basophils can form extracellular DNA traps (BETs) containing mitochondrial DNA and granule proteins. In this report, we provide evidence that, in spite of an apparent lack of phagocytic activity, basophils can kill bacteria through BET formation.

Formato

application/pdf

Identificador

http://boris.unibe.ch/71497/1/Basophils%20exhibit%20antibacterial%20activity%20through%20extracellular%20trap%20formation.pdf

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662 <http://dx.doi.org/10.1111/all.12662>

doi:10.7892/boris.71497

info:doi:10.1111/all.12662

info:pmid:26043360

urn:issn:0105-4538

Idioma(s)

eng

Publicador

Wiley-Blackwell

Relação

http://boris.unibe.ch/71497/

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662 <http://dx.doi.org/10.1111/all.12662>

Palavras-Chave #610 Medicine & health
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed