DNA triple-helix formation at pyrimidine-purine inversion sites
| Data(s) |
2001
|
|---|---|
| Resumo |
A systematic investigation of a series of triplex forming oligonucleotides (TFOs) containing alpha- and beta-thymidine, alpha- and beta-N7-hypoxanthine, and alpha- and beta- N7 and N9 aminopurine nucleosides, designed to bind to T-A inversion sites in DNA target sequences was performed. Data obtained from gel mobility assays indicate that t-A recognition in the antiparallel triple-helical binding motif is possible if the nucleoside alpha N9-aminopurine is used opposite to the inversion site in the TFO. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/68586/1/8824635.pdf Parel, S. P.; Marfurt, J.; Leumann, Christian (2001). DNA triple-helix formation at pyrimidine-purine inversion sites. Nucleosides, nucleotides & nucleic acids, 20(4-7), pp. 411-417. Taylor & Francis 10.1081/NCN-100002315 <http://dx.doi.org/10.1081/NCN-100002315> doi:10.7892/boris.68586 info:doi:10.1081/NCN-100002315 info:pmid:11563056 urn:issn:1525-7770 |
| Idioma(s) |
eng |
| Publicador |
Taylor & Francis |
| Relação |
http://boris.unibe.ch/68586/ |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Parel, S. P.; Marfurt, J.; Leumann, Christian (2001). DNA triple-helix formation at pyrimidine-purine inversion sites. Nucleosides, nucleotides & nucleic acids, 20(4-7), pp. 411-417. Taylor & Francis 10.1081/NCN-100002315 <http://dx.doi.org/10.1081/NCN-100002315> |
| Palavras-Chave | #570 Life sciences; biology #540 Chemistry |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
