Pyrrolidino-DNA
| Data(s) |
2003
|
|---|---|
| Resumo |
We synthesized pyrrolidino-C-nucleosides, incorporated them into oligodeoxynucleotides and investigated their pairing properties. The thermal duplex and triplex stabilities were measured. While triplex formation is destabilized in the case of pyrrolidino-pseudo-U and -T, pyrrolidino-pseudo-iso-C leads to an increase of the Tm value for third strand dissociation. Duplexes are destabilized with all pyrrolidino-C-nucleosides |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/68566/1/10833742.pdf Häberli, A.; Mayer, Alain; Leumann, Christian (2003). Pyrrolidino-DNA. Nucleosides, nucleotides & nucleic acids, 22(5-8), pp. 1187-1189. Taylor & Francis 10.1081/NCN-120022832 <http://dx.doi.org/10.1081/NCN-120022832> doi:10.7892/boris.68566 info:doi:10.1081/NCN-120022832 info:pmid:14565376 urn:issn:1525-7770 |
| Idioma(s) |
eng |
| Publicador |
Taylor & Francis |
| Relação |
http://boris.unibe.ch/68566/ |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Häberli, A.; Mayer, Alain; Leumann, Christian (2003). Pyrrolidino-DNA. Nucleosides, nucleotides & nucleic acids, 22(5-8), pp. 1187-1189. Taylor & Francis 10.1081/NCN-120022832 <http://dx.doi.org/10.1081/NCN-120022832> |
| Palavras-Chave | #570 Life sciences; biology #540 Chemistry |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
