Synthetic studies towards a novel, chemical stable, abasic site analogue of DNA
| Data(s) |
2003
|
|---|---|
| Resumo |
We synthesized the phosphinate 7 via photoaddition of methanol to the alpha, beta unsaturated deoxyribono lactone as the key step, followed by an Arbusov reaction for the introduction of phosphorous. Precursor 7 serves for the synthesis and incorporation into DNA of a novel chemically stable abasic site analogue that might act as an inhibitor for DNA glycosylases |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/68565/1/10833738.pdf Hirtz, C.; Leumann, Christian (2003). Synthetic studies towards a novel, chemical stable, abasic site analogue of DNA. Nucleosides, nucleotides & nucleic acids, 22(5-8), pp. 1203-1206. Taylor & Francis 10.1081/NCN-120022836 <http://dx.doi.org/10.1081/NCN-120022836> doi:10.7892/boris.68565 info:doi:10.1081/NCN-120022836 info:pmid:14565380 urn:issn:1525-7770 |
| Idioma(s) |
eng |
| Publicador |
Taylor & Francis |
| Relação |
http://boris.unibe.ch/68565/ |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Hirtz, C.; Leumann, Christian (2003). Synthetic studies towards a novel, chemical stable, abasic site analogue of DNA. Nucleosides, nucleotides & nucleic acids, 22(5-8), pp. 1203-1206. Taylor & Francis 10.1081/NCN-120022836 <http://dx.doi.org/10.1081/NCN-120022836> |
| Palavras-Chave | #570 Life sciences; biology #540 Chemistry |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
