A short, efficient synthesis of 2'-deoxypseudoisocytidine based on Heck-chemistry
| Data(s) |
2003
|
|---|---|
| Resumo |
A novel synthesis of 2'-deoxypseudoisocytidine as well as of its phosphoramidite building block for oligonucleotide synthesis is presented. The synthesis is based on Heck-coupling between N-protected pseudoisocytosine and a silyl protected furanoid glycal. With this procedure the corresponding phosphoramidite building block is obtained in 5 steps and an overall yield of 28%. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/68563/1/NCN-120025239.pdf Mayer, Alain; Leumann, Christian (2003). A short, efficient synthesis of 2'-deoxypseudoisocytidine based on Heck-chemistry. Nucleosides, nucleotides & nucleic acids, 22(10), pp. 1919-1925. Taylor & Francis 10.1081/NCN-120025239 <http://dx.doi.org/10.1081/NCN-120025239> doi:10.7892/boris.68563 info:doi:10.1081/NCN-120025239 info:pmid:14609231 urn:issn:1525-7770 |
| Idioma(s) |
eng |
| Publicador |
Taylor & Francis |
| Relação |
http://boris.unibe.ch/68563/ |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Mayer, Alain; Leumann, Christian (2003). A short, efficient synthesis of 2'-deoxypseudoisocytidine based on Heck-chemistry. Nucleosides, nucleotides & nucleic acids, 22(10), pp. 1919-1925. Taylor & Francis 10.1081/NCN-120025239 <http://dx.doi.org/10.1081/NCN-120025239> |
| Palavras-Chave | #570 Life sciences; biology #540 Chemistry |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
