Hydroxycyclopentanone derivatives from D-Mannose via ring closing metathesis: An improved synthesis of a key intermediate of Tricyclo-DNA


Autoria(s): Vonlanthen, David; Leumann, Christian
Data(s)

2003

Resumo

A large scale, 10 step synthesis of cyclopentanone 1 , starting from the chiral pool compound D-mannose, is described. The synthesis proceeds via a ring closing metathesis reaction as the key step in an overall yield of 23%. Cyclopentanone 1 is a central intermediate for the synthesis of tricyclo-DNA

Formato

application/pdf

Identificador

http://boris.unibe.ch/68561/8/s-2003-39177.pdf

Vonlanthen, David; Leumann, Christian (2003). Hydroxycyclopentanone derivatives from D-Mannose via ring closing metathesis: An improved synthesis of a key intermediate of Tricyclo-DNA. Synthesis - journal of synthetic organic chemistry, 2003(07), pp. 1087-1090. Thieme 10.1055/s-2003-39177 <http://dx.doi.org/10.1055/s-2003-39177>

doi:10.7892/boris.68561

info:doi:10.1055/s-2003-39177

urn:issn:0039-7881

Idioma(s)

eng

Publicador

Thieme

Relação

http://boris.unibe.ch/68561/

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Vonlanthen, David; Leumann, Christian (2003). Hydroxycyclopentanone derivatives from D-Mannose via ring closing metathesis: An improved synthesis of a key intermediate of Tricyclo-DNA. Synthesis - journal of synthetic organic chemistry, 2003(07), pp. 1087-1090. Thieme 10.1055/s-2003-39177 <http://dx.doi.org/10.1055/s-2003-39177>

Palavras-Chave #570 Life sciences; biology #540 Chemistry
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed