Of mice, macaques and men: scaling of virus dynamics and immune responses


Autoria(s): Althaus, Christian L
Data(s)

23/04/2015

Resumo

In this Opinion piece, I argue that the dynamics of viruses and the cellular immune response depend on the body size of the host. I use allometric scaling theory to interpret observed quantitative differences in the infection dynamics of lymphocytic choriomeningitis virus (LCMV) in mice (Mus musculus), simian immunodeficiency virus (SIV) in rhesus macaques (Macaca mulatta) and human immunodeficiency virus (HIV) in humans.

Formato

application/pdf

Identificador

http://boris.unibe.ch/68430/1/Althaus%20FrontMicrobiol%202015.pdf

Althaus, Christian L (2015). Of mice, macaques and men: scaling of virus dynamics and immune responses. Frontiers in Microbiology, 6, p. 355. Frontiers 10.3389/fmicb.2015.00355 <http://dx.doi.org/10.3389/fmicb.2015.00355>

doi:10.7892/boris.68430

info:doi:10.3389/fmicb.2015.00355

info:pmid:25954270

urn:issn:1664-302X

Idioma(s)

eng

Publicador

Frontiers

Relação

http://boris.unibe.ch/68430/

Direitos

info:eu-repo/semantics/openAccess

Fonte

Althaus, Christian L (2015). Of mice, macaques and men: scaling of virus dynamics and immune responses. Frontiers in Microbiology, 6, p. 355. Frontiers 10.3389/fmicb.2015.00355 <http://dx.doi.org/10.3389/fmicb.2015.00355>

Palavras-Chave #610 Medicine & health #360 Social problems & social services
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed