Long-Term Effects of the Treatment of Depressive Female Inpatients in a Naturalistic Study: Is Early Improvement a Valid Predictor of Outcome?
Data(s) |
30/06/2014
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Resumo |
Objectives: To examine the predictive value of early improvement for short- and long-term outcome in the treatment of depressive female inpatients and to explore the influence of comorbid disorders (CD). Methods: Archival data of a naturalistic sample of 277 female inpatients diagnosed with a depressive disorder was analyzed assessing the BDI at baseline, after 20 days and 30 days, posttreatment, and after 3 to 6 months at follow-up. Early improvement, defined as a decrease in the BDI score of at least 30% after 20 and after 30 days, and CD were analyzed using binary logistic regression. Results: Both early improvement definitions were predictive of remission at posttreatment. Early improvement after 30 days showed a sustained treatment effect in the follow-up phase, whereas early improvement after 20 days failed to show a persistent effect regarding remission at follow-up. CD were not significantly related neither at posttreatment nor at follow-up. At no time point CD moderated the prediction by early improvement. Conclusions: We show that early improvement is a valid predictor for short-term remission and at follow-up in an inpatient setting. CD did not predict outcome. Further studies are needed to identify patient subgroups amenable to more tailored treatments. |
Formato |
application/pdf |
Identificador |
http://boris.unibe.ch/66524/1/780237%282%29.pdf Zürcher-Hürlimann, Elian; Grosse Holtforth, Martin; Hermann, Ernst (2014). Long-Term Effects of the Treatment of Depressive Female Inpatients in a Naturalistic Study: Is Early Improvement a Valid Predictor of Outcome? Depression Research and Treatment, 2014(780237), pp. 1-8. Hindawi Publishing Corporation 10.1155/2014/780237 <http://dx.doi.org/10.1155/2014/780237> doi:10.7892/boris.66524 info:doi:10.1155/2014/780237 urn:issn:2090-1321 |
Idioma(s) |
eng |
Publicador |
Hindawi Publishing Corporation |
Relação |
http://boris.unibe.ch/66524/ |
Direitos |
info:eu-repo/semantics/openAccess |
Fonte |
Zürcher-Hürlimann, Elian; Grosse Holtforth, Martin; Hermann, Ernst (2014). Long-Term Effects of the Treatment of Depressive Female Inpatients in a Naturalistic Study: Is Early Improvement a Valid Predictor of Outcome? Depression Research and Treatment, 2014(780237), pp. 1-8. Hindawi Publishing Corporation 10.1155/2014/780237 <http://dx.doi.org/10.1155/2014/780237> |
Palavras-Chave | #610 Medicine & health #150 Psychology |
Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |