Localized Epidermal Cysts as a Radiation Recall Phenomenon in a Melanoma Patient Treated with Radiotherapy and the BRAF Inhibitor Vemurafenib


Autoria(s): Houriet, Carine; Klass, Natalie Désirée; Beltraminelli, Helmut; Borradori, Luca; Oberholzer, Patrick Antony
Data(s)

01/09/2014

Resumo

BRAF inhibitors are broadly used for metastatic melanoma with BRAF mutations. Their use results in various cutaneous side effects, such as the development of keratoacanthomas and squamous cell carcinomas. We report a patient with metastatic melanoma treated with vemurafenib who developed dozens of histologically confirmed epidermal cysts within 2 months after initiation of vemurafenib administration. The cystic lesions were observed only in the localized area where a large exophytic melanoma tumor mass had been previously irradiated. Localized epidermal cysts may constitute an unusual radiation recall reaction in patients treated with BRAF inhibitors.

Formato

application/pdf

Identificador

http://boris.unibe.ch/60536/1/367708.pdf

Houriet, Carine; Klass, Natalie Désirée; Beltraminelli, Helmut; Borradori, Luca; Oberholzer, Patrick Antony (2014). Localized Epidermal Cysts as a Radiation Recall Phenomenon in a Melanoma Patient Treated with Radiotherapy and the BRAF Inhibitor Vemurafenib. Case reports in dermatology, 6(3), pp. 213-217. Karger 10.1159/000367708 <http://dx.doi.org/10.1159/000367708>

doi:10.7892/boris.60536

info:doi:10.1159/000367708

info:pmid:25408648

urn:issn:1662-6567

Idioma(s)

eng

Publicador

Karger

Relação

http://boris.unibe.ch/60536/

Direitos

info:eu-repo/semantics/openAccess

Fonte

Houriet, Carine; Klass, Natalie Désirée; Beltraminelli, Helmut; Borradori, Luca; Oberholzer, Patrick Antony (2014). Localized Epidermal Cysts as a Radiation Recall Phenomenon in a Melanoma Patient Treated with Radiotherapy and the BRAF Inhibitor Vemurafenib. Case reports in dermatology, 6(3), pp. 213-217. Karger 10.1159/000367708 <http://dx.doi.org/10.1159/000367708>

Palavras-Chave #610 Medicine & health
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed