Designed cell penetrating peptide dendrimers efficiently internalize cargo into cells
| Data(s) |
2014
|
|---|---|
| Resumo |
Redesigning linear cell penetrating peptides (CPPs) into a multi-branched topology with short dipeptide branches gave cell penetrating peptide dendrimers (CPPDs) with higher cell penetration, lower toxicity and hemolysis and higher serum stability than linear CPPs. Their use is demonstrated by delivering a cytotoxic peptide and paclitaxel into cells. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/60006/1/c4cc02780a-3.pdf Eggimann, Gabriela A.; Blattes, Emilyne; Buschor, Stefanie; Biswas, Rasomoy; Kammer, Stephan M.; Darbre, Tamis; Reymond, Jean-Louis (2014). Designed cell penetrating peptide dendrimers efficiently internalize cargo into cells. Chemical communications, 50(55), pp. 7254-7257. Royal Society of Chemistry 10.1039/C4CC02780A <http://dx.doi.org/10.1039/C4CC02780A> doi:10.7892/boris.60006 info:doi:10.1039/C4CC02780A urn:issn:1359-7345 |
| Idioma(s) |
eng |
| Publicador |
Royal Society of Chemistry |
| Relação |
http://boris.unibe.ch/60006/ |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Eggimann, Gabriela A.; Blattes, Emilyne; Buschor, Stefanie; Biswas, Rasomoy; Kammer, Stephan M.; Darbre, Tamis; Reymond, Jean-Louis (2014). Designed cell penetrating peptide dendrimers efficiently internalize cargo into cells. Chemical communications, 50(55), pp. 7254-7257. Royal Society of Chemistry 10.1039/C4CC02780A <http://dx.doi.org/10.1039/C4CC02780A> |
| Palavras-Chave | #570 Life sciences; biology #540 Chemistry #610 Medicine & health |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
