The Biological Side of Water-Soluble Arene Ruthenium Assemblies
Data(s) |
2014
|
---|---|
Resumo |
This review article covers the synthetic strategies, structural aspects, and host-guest properties of ruthenium metalla-assemblies, with a special focus on their use as drug delivery vectors. The two-dimensional metalla-rectangles show interesting host-guest possibilities but seem less appropriate for being used as drug carriers. On the other hand, metalla-prisms allow encapsulation and possible targeted release of bioactive molecules and consequently show some potential as drug delivery vectors. The reactivity of these metalla-prisms can be fine-tuned to allow a fine control of the guest’s release. The larger metalla-cubes can be used to stabilize the formation of G-quadruplex DNA and can be used to encapsulate and release photoactive molecules such as porphins. These metalla-assemblies demonstrate great prospective in photodynamic therapy. |
Formato |
application/pdf |
Identificador |
http://boris.unibe.ch/58844/1/589686.pdf Therrien, Bruno; Furrer, Julien (2014). The Biological Side of Water-Soluble Arene Ruthenium Assemblies. Advances in chemistry, 2014, pp. 1-20. Hindawi 10.1155/2014/589686 <http://dx.doi.org/10.1155/2014/589686> doi:10.7892/boris.58844 info:doi:10.1155/2014/589686 urn:issn:2356-6612 |
Idioma(s) |
eng |
Publicador |
Hindawi |
Relação |
http://boris.unibe.ch/58844/ |
Direitos |
info:eu-repo/semantics/openAccess |
Fonte |
Therrien, Bruno; Furrer, Julien (2014). The Biological Side of Water-Soluble Arene Ruthenium Assemblies. Advances in chemistry, 2014, pp. 1-20. Hindawi 10.1155/2014/589686 <http://dx.doi.org/10.1155/2014/589686> |
Palavras-Chave | #570 Life sciences; biology #540 Chemistry |
Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |