Tuning Molecular Recognition of RNA and DNA via Sugar Modification


Autoria(s): Leumann, Christian J.
Data(s)

2005

Resumo

This minireview highlights three aspects of our recent work in the area of sugar modified oligonucleotide analogues. It provides an overview over recent results on the conformationally constrained analogue tricyclo-DNA with special emphasis of its antisense properties, it summarizes results on triple-helix forming oligodeoxynucleotides containing pyrrolidino-nucleosides with respect to DNA recognition via the dual recognition mode, and it highlights the advantageous application of the orthogonal oligonucleotidic pairing system homo-DNA in molecular beacons for DNA diagnostics

Formato

application/pdf

Identificador

http://boris.unibe.ch/53107/1/Chimia_105.pdf

Leumann, Christian J. (2005). Tuning Molecular Recognition of RNA and DNA via Sugar Modification. CHIMIA, 59(11), pp. 776-779. Bern: Schweizerische Chemische Gesellschaft

doi:10.7892/boris.53107

urn:issn:0009-4293

Idioma(s)

eng

Publicador

Schweizerische Chemische Gesellschaft

Relação

http://boris.unibe.ch/53107/

Direitos

info:eu-repo/semantics/openAccess

Fonte

Leumann, Christian J. (2005). Tuning Molecular Recognition of RNA and DNA via Sugar Modification. CHIMIA, 59(11), pp. 776-779. Bern: Schweizerische Chemische Gesellschaft

Palavras-Chave #570 Life sciences; biology #540 Chemistry
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed