Mineralization of calcium phosphate crystals in starch template inducing a brushite kidney stone biomimetic composite
| Data(s) |
18/03/2013
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|---|---|
| Resumo |
Dicalcium phosphate dihydrate (brushite) and octacalcium phosphate (OCP) crystals are precursors of hydroxyapatite (HAp) for tooth enamel, dentine, and bones formation in living organisms. Here, we introduce a new method for biomimicking brushite and OCP in starch using single and double diffusion techniques. Brushite and OCP crystals were grown by precipitation in starch after gelation. The obtained materials were analyzed by infrared spectroscopy (IR), scanning electron microscopy (SEM), X-ray diffraction (XRD), and confocal laser scanning microscopy (CLSM). IR spectra demonstrate starch inclusion by peak shifts in the 2900–3500 cm–1 region. SEM showed two different morphologies: plate-shaped and needle-like crystals. Calcium phosphate/starch aggregates bear strong resemblance to prismatic brushite kidney stones. This may open up a clue to understand the mechanism of kidney stone formation. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/46848/1/cg4002434.pdf Parvinzadeh Gashti, Mazeyar; Stir, Manuela; Bourquin, Marc; Hulliger, Jurg (2013). Mineralization of calcium phosphate crystals in starch template inducing a brushite kidney stone biomimetic composite. Crystal growth & design, 13(5), pp. 2166-2173. American Chemical Society 10.1021/cg4002434 <http://dx.doi.org/10.1021/cg4002434> doi:10.7892/boris.46848 info:doi:10.1021/cg4002434 urn:issn:1528-7483 |
| Idioma(s) |
eng |
| Publicador |
American Chemical Society |
| Relação |
http://boris.unibe.ch/46848/ |
| Direitos |
info:eu-repo/semantics/restrictedAccess |
| Fonte |
Parvinzadeh Gashti, Mazeyar; Stir, Manuela; Bourquin, Marc; Hulliger, Jurg (2013). Mineralization of calcium phosphate crystals in starch template inducing a brushite kidney stone biomimetic composite. Crystal growth & design, 13(5), pp. 2166-2173. American Chemical Society 10.1021/cg4002434 <http://dx.doi.org/10.1021/cg4002434> |
| Palavras-Chave | #570 Life sciences; biology #540 Chemistry |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
