SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/H⁺ exchangers
| Data(s) |
01/06/2013
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|---|---|
| Resumo |
This brief review of the human Na/H exchanger gene family introduces a new classification with three subgroups to the SLC9 gene family. Progress in the structure and function of this gene family is reviewed with structure based on homology to the bacterial Na/H exchanger NhaA. Human diseases which result from genetic abnormalities of the SLC9 family are discussed although the exact role of these transporters in causing any disease is not established, other than poorly functioning NHE3 in congenital Na diarrhea. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/41104/1/SLC9_DFuster.pdf Donowitz, Mark; Ming Tse, C.; Fuster, Daniel Guido (2013). SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/H⁺ exchangers. Molecular aspects of medicine, 34(2-3), pp. 236-251. Elsevier 10.1016/j.mam.2012.05.001 <http://dx.doi.org/10.1016/j.mam.2012.05.001> doi:10.7892/boris.41104 info:doi:10.1016/j.mam.2012.05.001 info:pmid:23506868 urn:issn:0098-2997 |
| Idioma(s) |
eng |
| Publicador |
Elsevier |
| Relação |
http://boris.unibe.ch/41104/ |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Donowitz, Mark; Ming Tse, C.; Fuster, Daniel Guido (2013). SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/H⁺ exchangers. Molecular aspects of medicine, 34(2-3), pp. 236-251. Elsevier 10.1016/j.mam.2012.05.001 <http://dx.doi.org/10.1016/j.mam.2012.05.001> |
| Palavras-Chave | #610 Medicine & health #570 Life sciences; biology |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
