Immune recovery after starting ART in HIV-infected patients presenting and not presenting with tuberculosis in South Africa
| Data(s) |
01/05/2013
|
|---|---|
| Resumo |
We studied the immune response after starting antiretroviral treatment (ART) in 15,646 HIV-infected patients with or without tuberculosis (TB) at presentation in 3 ART programs in South Africa between 2003 and 2010. Patients presenting with TB had similar increases in CD4 cells compared with all other patients (adjusted difference 4.9 cells/µL per 6 months, 95% confidence interval: 0.2 to 9.7). Younger age, advanced clinical stage, female sex, and lower CD4 cell count at ART start were all associated with steeper CD4 slopes. In South Africa, HIV-infected patients presenting with TB experience immune recovery after starting ART that is no worse than in other patients. |
| Formato |
application/pdf application/pdf |
| Identificador |
http://boris.unibe.ch/40854/1/Schomaker%20JAIDS%202013.pdf http://boris.unibe.ch/40854/2/Schomaker%20JAIDS%202013.pdf Schomaker, Michael; Egger, Matthias; Maskew, Mhairi; Garone, Daniela; Prozesky, Hans; Hoffmann, Christopher J.; Boulle, Andrew; Fenner, Lukas (2013). Immune recovery after starting ART in HIV-infected patients presenting and not presenting with tuberculosis in South Africa. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 63(1), pp. 142-145. Lippincott Williams & Wilkins 10.1097/QAI.0b013e318288b39d <http://dx.doi.org/10.1097/QAI.0b013e318288b39d> doi:10.7892/boris.40854 info:doi:10.1097/QAI.0b013e318288b39d info:pmid:23364513 urn:issn:0894-9255 |
| Idioma(s) |
eng |
| Publicador |
Lippincott Williams & Wilkins |
| Relação |
http://boris.unibe.ch/40854/ |
| Direitos |
info:eu-repo/semantics/openAccess info:eu-repo/semantics/restrictedAccess |
| Fonte |
Schomaker, Michael; Egger, Matthias; Maskew, Mhairi; Garone, Daniela; Prozesky, Hans; Hoffmann, Christopher J.; Boulle, Andrew; Fenner, Lukas (2013). Immune recovery after starting ART in HIV-infected patients presenting and not presenting with tuberculosis in South Africa. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 63(1), pp. 142-145. Lippincott Williams & Wilkins 10.1097/QAI.0b013e318288b39d <http://dx.doi.org/10.1097/QAI.0b013e318288b39d> |
| Palavras-Chave | #610 Medicine & health #360 Social problems & social services |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
