A regioselective palladium-free protocol for accessing unsymmetrical biaryls through ring transformation of 6-aryl-~-pyrones
| Data(s) |
15/11/2007
15/11/2007
2007
|
|---|---|
| Resumo |
A regioselective synthesis of unsymmetrical biaryls with electron withdrawing or donating substituents is described and illustrated by carbanion-induced ring transfonnation of 6-aryl-a-pyrones with methoxyacetone in excellent yield. Our methodology is an alternative to classical organometal-catalyzed aryl-aryl coupling reactions and can be applied to the synthesis of functionally demanding naphthyl biaryls for the development of new ligands for asymetric synthesis |
| Formato |
92259 bytes application/pdf |
| Identificador |
Tetrahedron Letters 48 (2007) 7283-7286 |
| Idioma(s) |
en |
| Relação |
C.D.R.I. Communication No. 7255 |
| Palavras-Chave | #asymetric synthesis #regioselective #6-aryl-a-pyrones #carbanion-induced ring |
| Tipo |
Article |
