Synthesis of bicyclo-DNA nucleosides with additional functionalization in the carbocyclic ring
| Data(s) |
01/04/2008
|
|---|---|
| Resumo |
Two novel bicyclo nucleoside isomers carrying the base thymine in the furanose ring and an ester substituent in the carbocyclic ring were synthesized from a common bicyclic sugar precursor via a cyclopropanation/fragmentation pathway in nine steps. The relative configuration of the ester substituent in both isomers as well as the anomeric configuration in one nucleoside was determined by 1H-NMR difference NOE spectroscopy. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/31037/1/s19.pdf Luisier, Samuel; Leumann, Christian J. (2008). Synthesis of bicyclo-DNA nucleosides with additional functionalization in the carbocyclic ring. CHIMIA, 62(4), pp. 270-272. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2008.270 <http://dx.doi.org/10.2533/chimia.2008.270> doi:10.7892/boris.31037 info:doi:10.2533/chimia.2008.270 urn:issn:0009-4293 |
| Idioma(s) |
eng |
| Publicador |
Schweizerische Chemische Gesellschaft |
| Relação |
http://boris.unibe.ch/31037/ |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Luisier, Samuel; Leumann, Christian J. (2008). Synthesis of bicyclo-DNA nucleosides with additional functionalization in the carbocyclic ring. CHIMIA, 62(4), pp. 270-272. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2008.270 <http://dx.doi.org/10.2533/chimia.2008.270> |
| Palavras-Chave | #500 Science #540 Chemistry #570 Life sciences; biology |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion NonPeerReviewed |
