The GPVI - Fc Fusion Protein Revacept Reduces Thrombus Formation and Improves Vascular Dysfunction in Atherosclerosis without Any Impact on Bleeding Times
| Data(s) |
2013
|
|---|---|
| Resumo |
Glycoprotein VI (GPVI) is a key platelet receptor which mediates plaque-induced platelet activation and consecutive atherothrombosis, but GPVI is also involved in platelet-mediated atheroprogression. Therefore, interference in GPVI-mediated platelet activation has the potential to combine short-term and long-term beneficial effects, specificity and safety especially regarding bleeding complications. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/17470/1/fetchObject.pdf Ungerer, Martin; Li, Zhongmin; Baumgartner, Christine; Goebel, Silvia; Vogelmann, Jasmin; Holthoff, Hans-Peter; Gawaz, Meinrad; Münch, Götz (2013). The GPVI - Fc Fusion Protein Revacept Reduces Thrombus Formation and Improves Vascular Dysfunction in Atherosclerosis without Any Impact on Bleeding Times. PLoS ONE, 8(8), e71193. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0071193 <http://dx.doi.org/10.1371/journal.pone.0071193> doi:10.7892/boris.17470 info:doi:10.1371/journal.pone.0071193 info:pmid:23951109 urn:issn:1932-6203 |
| Idioma(s) |
eng |
| Publicador |
Public Library of Science |
| Relação |
http://boris.unibe.ch/17470/ |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Ungerer, Martin; Li, Zhongmin; Baumgartner, Christine; Goebel, Silvia; Vogelmann, Jasmin; Holthoff, Hans-Peter; Gawaz, Meinrad; Münch, Götz (2013). The GPVI - Fc Fusion Protein Revacept Reduces Thrombus Formation and Improves Vascular Dysfunction in Atherosclerosis without Any Impact on Bleeding Times. PLoS ONE, 8(8), e71193. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0071193 <http://dx.doi.org/10.1371/journal.pone.0071193> |
| Palavras-Chave | #610 Medicine & health |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |
