Neural progenitor cells regulate microglia functions and activity


Autoria(s): Mosher, Kira I.; Andres, Robert H.; Fukuhara, Takeshi; Bieri, Gregor; Hasegawa-Moriyama, Maiko; He, Yingbo; Guzman, Raphael; Wyss-Coray, Tony
Data(s)

2012

Resumo

We found mouse neural progenitor cells (NPCs) to have a secretory protein profile distinct from other brain cells and to modulate microglial activation, proliferation and phagocytosis. NPC-derived vascular endothelial growth factor was necessary and sufficient to exert at least some of these effects in mice. Thus, neural precursor cells may not only be shaped by microglia, but also regulate microglia functions and activity.

Formato

application/pdf

Identificador

http://boris.unibe.ch/14843/1/Neural%20Progenitor%20Cells%20Regulate%20Microglia%20Functions%20and%20Activity%20States.pdf

Mosher, Kira I.; Andres, Robert H.; Fukuhara, Takeshi; Bieri, Gregor; Hasegawa-Moriyama, Maiko; He, Yingbo; Guzman, Raphael; Wyss-Coray, Tony (2012). Neural progenitor cells regulate microglia functions and activity. Nature neuroscience, 15(11), pp. 1485-1487. New York, N.Y.: Nature America 10.1038/nn.3233 <http://dx.doi.org/10.1038/nn.3233>

doi:10.7892/boris.14843

info:doi:10.1038/nn.3233

info:pmid:23086334

urn:issn:1097-6256

Idioma(s)

eng

Publicador

Nature America

Relação

http://boris.unibe.ch/14843/

Direitos

info:eu-repo/semantics/openAccess

Fonte

Mosher, Kira I.; Andres, Robert H.; Fukuhara, Takeshi; Bieri, Gregor; Hasegawa-Moriyama, Maiko; He, Yingbo; Guzman, Raphael; Wyss-Coray, Tony (2012). Neural progenitor cells regulate microglia functions and activity. Nature neuroscience, 15(11), pp. 1485-1487. New York, N.Y.: Nature America 10.1038/nn.3233 <http://dx.doi.org/10.1038/nn.3233>

Palavras-Chave #610 Medicine & health
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed