Neural progenitor cells regulate microglia functions and activity
Data(s) |
2012
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Resumo |
We found mouse neural progenitor cells (NPCs) to have a secretory protein profile distinct from other brain cells and to modulate microglial activation, proliferation and phagocytosis. NPC-derived vascular endothelial growth factor was necessary and sufficient to exert at least some of these effects in mice. Thus, neural precursor cells may not only be shaped by microglia, but also regulate microglia functions and activity. |
Formato |
application/pdf |
Identificador |
Mosher, Kira I.; Andres, Robert H.; Fukuhara, Takeshi; Bieri, Gregor; Hasegawa-Moriyama, Maiko; He, Yingbo; Guzman, Raphael; Wyss-Coray, Tony (2012). Neural progenitor cells regulate microglia functions and activity. Nature neuroscience, 15(11), pp. 1485-1487. New York, N.Y.: Nature America 10.1038/nn.3233 <http://dx.doi.org/10.1038/nn.3233> doi:10.7892/boris.14843 info:doi:10.1038/nn.3233 info:pmid:23086334 urn:issn:1097-6256 |
Idioma(s) |
eng |
Publicador |
Nature America |
Relação |
http://boris.unibe.ch/14843/ |
Direitos |
info:eu-repo/semantics/openAccess |
Fonte |
Mosher, Kira I.; Andres, Robert H.; Fukuhara, Takeshi; Bieri, Gregor; Hasegawa-Moriyama, Maiko; He, Yingbo; Guzman, Raphael; Wyss-Coray, Tony (2012). Neural progenitor cells regulate microglia functions and activity. Nature neuroscience, 15(11), pp. 1485-1487. New York, N.Y.: Nature America 10.1038/nn.3233 <http://dx.doi.org/10.1038/nn.3233> |
Palavras-Chave | #610 Medicine & health |
Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |