Influence of reported study design characteristics on intervention effect estimates from randomised controlled trials: combined analysis of meta-epidemiological studies
| Data(s) |
2012
|
|---|---|
| Resumo |
The design of randomised controlled trials (RCTs) should incorporate characteristics (such as concealment of randomised allocation and blinding of participants and personnel) that avoid biases resulting from lack of comparability of the intervention and control groups. Empirical evidence suggests that the absence of such characteristics leads to biased intervention effect estimates, but the findings of different studies are not consistent. |
| Formato |
application/pdf |
| Identificador |
http://boris.unibe.ch/13989/1/Savovic%20HealthTechnolAssess%202012.pdf Savović, J; Jones, He; Altman, Dg; Harris, Rj; Jűni, P; Pildal, J; Als-Nielsen, B; Balk, Em; Gluud, C; Gluud, Ll; Ioannidis, Jpa; Schulz, Kf; Beynon, R; Welton, N; Wood, L; Moher, D; Deeks, Jj; Sterne, Jac (2012). Influence of reported study design characteristics on intervention effect estimates from randomised controlled trials: combined analysis of meta-epidemiological studies. Health technology assessment, 16(35), pp. 1-82. Southampton, UK: National Coordinating Centre for Health Technology Assessment 10.3310/hta16350 <http://dx.doi.org/10.3310/hta16350> doi:10.7892/boris.13989 info:doi:10.3310/hta16350 info:pmid:22989478 urn:issn:1366-5278 |
| Idioma(s) |
eng |
| Publicador |
National Coordinating Centre for Health Technology Assessment |
| Relação |
http://boris.unibe.ch/13989/ |
| Direitos |
info:eu-repo/semantics/openAccess |
| Fonte |
Savović, J; Jones, He; Altman, Dg; Harris, Rj; Jűni, P; Pildal, J; Als-Nielsen, B; Balk, Em; Gluud, C; Gluud, Ll; Ioannidis, Jpa; Schulz, Kf; Beynon, R; Welton, N; Wood, L; Moher, D; Deeks, Jj; Sterne, Jac (2012). Influence of reported study design characteristics on intervention effect estimates from randomised controlled trials: combined analysis of meta-epidemiological studies. Health technology assessment, 16(35), pp. 1-82. Southampton, UK: National Coordinating Centre for Health Technology Assessment 10.3310/hta16350 <http://dx.doi.org/10.3310/hta16350> |
| Palavras-Chave | #610 Medicine & health |
| Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion NonPeerReviewed |
