miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner


Autoria(s): Bandi, Nora; Vassella, Erik
Data(s)

2011

Resumo

microRNAs (miRNAs) are small non-coding RNAs that are frequently involved in carcinogenesis. Although many miRNAs form part of integrated networks, little information is available how they interact with each other to control cellular processes. miR-34a and miR-15a/16 are functionally related; they share common targets and control similar processes including G1-S cell cycle progression and apoptosis. The aim of this study was to investigate the combined action of miR-34a and miR-15a/16 in non-small cell lung cancer (NSCLC) cells.

Formato

application/pdf

Identificador

http://boris.unibe.ch/5488/1/1476-4598-10-55.pdf

Bandi, Nora; Vassella, Erik (2011). miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. Molecular cancer, 10, p. 55. London: BioMed Central 10.1186/1476-4598-10-55 <http://dx.doi.org/10.1186/1476-4598-10-55>

doi:10.7892/boris.5488

info:doi:10.1186/1476-4598-10-55

info:pmid:21575235

urn:issn:1476-4598

Idioma(s)

eng

Publicador

BioMed Central

Relação

http://boris.unibe.ch/5488/

Direitos

info:eu-repo/semantics/openAccess

Fonte

Bandi, Nora; Vassella, Erik (2011). miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. Molecular cancer, 10, p. 55. London: BioMed Central 10.1186/1476-4598-10-55 <http://dx.doi.org/10.1186/1476-4598-10-55>

Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed