The protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in human
Data(s) |
2010
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Resumo |
Paraneoplastic pemphigus (PNP) is a devastating autoimmune blistering disease, involving mucocutaneous and internal organs, and associated with underlying neoplasms. PNP is characterized by the production of autoantibodies targeting proteins of the plakin and cadherin families involved in maintenance of cell architecture and tissue cohesion. Nevertheless, the identity of an antigen of Mr 170,000 (p170), thought to be critical in PNP pathogenesis, has remained unknown. |
Formato |
application/pdf |
Identificador |
http://boris.unibe.ch/2261/1/fetchObject.pdf Schepens, Isabelle; Jaunin, Fabienne; Begre, Nadja; Läderach, Ursula; Marcus, Katrin; Hashimoto, Takashi; Favre, Bertrand; Borradori, Luca (2010). The protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in human. PLoS ONE, 5(8), e12250. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0012250 <http://dx.doi.org/10.1371/journal.pone.0012250> doi:10.7892/boris.2261 info:doi:10.1371/journal.pone.0012250 info:pmid:20805888 urn:issn:1932-6203 |
Idioma(s) |
eng |
Publicador |
Public Library of Science |
Relação |
http://boris.unibe.ch/2261/ |
Direitos |
info:eu-repo/semantics/openAccess |
Fonte |
Schepens, Isabelle; Jaunin, Fabienne; Begre, Nadja; Läderach, Ursula; Marcus, Katrin; Hashimoto, Takashi; Favre, Bertrand; Borradori, Luca (2010). The protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in human. PLoS ONE, 5(8), e12250. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0012250 <http://dx.doi.org/10.1371/journal.pone.0012250> |
Palavras-Chave | #610 Medicine & health |
Tipo |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed |