Osteoporosis and bisphosphonates-related osteonecrosis of the jaw: Not just a sporadic coincidence - a multi-centre study


Autoria(s): Otto, Sven; Abu-Id, Mario Hakim; Fedele, Stefano; Warnke, Patrick H; Becker, Stephan T; Kolk, Andreas; Mücke, Thomas; Mast, Gerson; Köhnke, Robert; Volkmer, Elias; Haasters, Florian; Lieger, Olivier; Iizuka, Tateyuki; Porter, Stephen; Campisi, Giuseppina; Colella, Giuseppe; Ploder, Oliver; Neff, Andreas; Wiltfang, Jörg; Ehrenfeld, Michael; Kreusch, Thomas; Wolff, Klaus-Dietrich; Stürzenbaum, Stephen R; Schieker, Matthias; Pautke, Christoph
Data(s)

2011

Resumo

Bisphosphonates (BPs) are powerful drugs that inhibit bone metabolism. Adverse side effects are rare but potentially severe such as bisphosphonate-related osteonecrosis of the jaw (BRONJ). To date, research has primarily focused on the development and progression of BRONJ in cancer patients with bone metastasis, who have received high dosages of BPs intravenously. However, a potential dilemma may arise from a far larger cohort, namely the millions of osteoporosis patients on long-term oral BP therapy.

Formato

application/pdf

Identificador

http://boris.unibe.ch/443/1/1-s2.0-S1010518210001307-main.pdf

Otto, Sven; Abu-Id, Mario Hakim; Fedele, Stefano; Warnke, Patrick H; Becker, Stephan T; Kolk, Andreas; Mücke, Thomas; Mast, Gerson; Köhnke, Robert; Volkmer, Elias; Haasters, Florian; Lieger, Olivier; Iizuka, Tateyuki; Porter, Stephen; Campisi, Giuseppina; Colella, Giuseppe; Ploder, Oliver; Neff, Andreas; Wiltfang, Jörg; Ehrenfeld, Michael; ... (2011). Osteoporosis and bisphosphonates-related osteonecrosis of the jaw: Not just a sporadic coincidence - a multi-centre study. Journal of cranio-maxillo-facial surgery, 39(4), pp. 272-277. Oxford: Elsevier 10.1016/j.jcms.2010.05.009 <http://dx.doi.org/10.1016/j.jcms.2010.05.009>

doi:10.7892/boris.443

info:doi:10.1016/j.jcms.2010.05.009

info:pmid:20580566

urn:issn:1010-5182

Idioma(s)

eng

Publicador

Elsevier

Relação

http://boris.unibe.ch/443/

http://www.sciencedirect.com/science/article/pii/S1010518210001307#

Direitos

info:eu-repo/semantics/restrictedAccess

Fonte

Otto, Sven; Abu-Id, Mario Hakim; Fedele, Stefano; Warnke, Patrick H; Becker, Stephan T; Kolk, Andreas; Mücke, Thomas; Mast, Gerson; Köhnke, Robert; Volkmer, Elias; Haasters, Florian; Lieger, Olivier; Iizuka, Tateyuki; Porter, Stephen; Campisi, Giuseppina; Colella, Giuseppe; Ploder, Oliver; Neff, Andreas; Wiltfang, Jörg; Ehrenfeld, Michael; ... (2011). Osteoporosis and bisphosphonates-related osteonecrosis of the jaw: Not just a sporadic coincidence - a multi-centre study. Journal of cranio-maxillo-facial surgery, 39(4), pp. 272-277. Oxford: Elsevier 10.1016/j.jcms.2010.05.009 <http://dx.doi.org/10.1016/j.jcms.2010.05.009>

Palavras-Chave #610 Medicine & health
Tipo

info:eu-repo/semantics/article

info:eu-repo/semantics/publishedVersion

PeerReviewed