Synthetic studies towards a new fulvestrant analogue
| Contribuinte(s) |
Righi, Paolo Barrett, Anthony |
|---|---|
| Data(s) |
23/03/2016
31/12/1969
|
| Resumo |
A study towards the synthesis of a new fulvestrant analogue with improved bioavailability was carried out. In this work a twelve-step synthetic route starting from β-estradiol was optimized and a palladium (Pd)-catalyzed endo-selective Heck reaction for the functionalization of an advanced intermediate was investigated. |
| Formato |
application/pdf |
| Identificador |
Geminiani, Lorenzo (2016) Synthetic studies towards a new fulvestrant analogue. [Laurea magistrale], Università di Bologna, Corso di Studio in Chimica industriale [LM-DM270] <http://amslaurea.unibo.it/view/cds/CDS0884/> |
| Relação |
http://amslaurea.unibo.it/10004/ |
| Direitos |
Free to read |
| Palavras-Chave | #organic synthesis steroids estradiol estrogen fulvestrant bioavailability faslodex endo-selective palladium-catalyzed Heck reaction #Chimica industriale [LM-DM270] #cds :: 0884 :: Chimica industriale [LM-DM270] #sessione :: terza |
| Tipo |
PeerReviewed info:eu-repo/semantics/masterThesis |
| Idioma(s) |
en |
| Publicador |
Alma Mater Studiorum - Università di Bologna |
