Structural and vibrational study of 8-hydroxyquinoline-2-carboxaldehyde isonicotinoyl hydrazone: a potential metal-protein attenuating compound (MPAC) for the treatment of Alzheimer's disease
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
|---|---|
| Data(s) |
30/05/2014
30/05/2014
01/12/2013
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| Resumo |
A comprehensive structural and vibrational study of the potential metal-protein attenuating compound 8-hydroxyquinoline-2-carboxaldehyde isonicotinoyl hydrazone is reported. X-ray diffraction data, as well as FT-IR and Raman frequencies, were compared with the respective theoretical values obtained from DFT calculations. Theory agrees well with experiment. In this context, an attempt of total assignment concerning the FT-IR and Raman spectra of the title compound was performed, shedding new light on previous partial assignments published elsewhere. CNPq CAPES FAPEMIG |
| Identificador |
Spectrochimica Acta A, Amsterdam : Elsevier BV, v. 116, p. 41-48, Dec. 2013 1386-1425 http://www.producao.usp.br/handle/BDPI/45154 10.1016/j.saa.2013.06.105 |
| Idioma(s) |
eng |
| Publicador |
Elsevier BV Amsterdam |
| Relação |
Spectrochimica Acta A |
| Direitos |
restrictedAccess Copyright Elsevier B. V. |
| Palavras-Chave | #Vibrational spectroscopy #XRD #DFT calculations #Alzheimer’s disease #Isoniazid #DOENÇA DE ALZHEIMER #PROTEÍNAS (ESTUDO) #DIFRAÇÃO POR RAIOS X |
| Tipo |
article original article publishedVersion |
