Stopping power and depth dose profile of H+ and He+ ion beams in hydroxyapatite thin films.
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
25/04/2014
25/04/2014
20/05/2013
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Resumo |
Hadron therapy is a promising technique to treat deep-seated tumors. For an accurate treatment planning, the energy deposition in the soft and hard human tissue must be well known. Water has been usually employed as a phantom of soft tissues, but other biomaterials, such as hydroxyapatite (HAp), used as bone substitute, are also relevant as a phantom for hard tissues. The stopping power of HAp for H+ and He+ beams has been studied experimentally and theoretically. The measurements have been done using the Rutherford backscattering technique in an energy range of 450-2000 keV for H+ and of 400-5000 keV for He+ projectiles. The theoretical calculations are based in the dielectric formulation together with the MELF-GOS (Mermin Energy-Loss Function – Generalized Oscillator Strengths) method [1] to describe the target excitation spectrum. A quite good agreement between the experimental data and the theoretical results has been found. The depth dose profile of H+ and He+ ion beams in HAp has been simulated by the SEICS (Simulation of Energetic Ions and Clusters through Solids) code [2], which incorporates the electronic stopping force due to the energy loss by collisions with the target electrons, including fluctuations due to the energy-loss straggling, the multiple elastic scattering with the target nuclei, with their corresponding nuclear energy loss, and the dynamical charge-exchange processes in the projectile charge state. The energy deposition by H+ and He+ as a function of the depth are compared, at several projectile energies, for HAp and liquid water, showing important differences. European Regional Development Fund |
Identificador |
Nano-IBCT Conference, 2nd., 2013, Sopot. http://www.producao.usp.br/handle/BDPI/44659 http://nano-ibct2013.mif.pg.gda.pl/files/nano-ibct_2013_boa.pdf |
Idioma(s) |
eng |
Publicador |
Gdańsk University of Technology Sopot |
Relação |
Nano-IBCT Conference, Nanoscale Insights into Ion Beam Cancer Therapy, 2nd |
Direitos |
openAccess P. de Vera |
Palavras-Chave | #Thin films #Hydroxyapatite #Hadron therapy #Filmes finos #Hidroxiapatita #Elétrons |
Tipo |
conferenceObject Resumo |