Synthetic biology: a novel approach for the construction of industrial microorganisms


Autoria(s): Hranueli, Daslav; Starcevic, Antonio; Zucko, Jurica; Rojas, Juan Diego; Diminic, Janko; Baranasic, Damir; Gacesa, Ranko; Maldonado, Gabriel Padilla; Long, Paul F.; Cullum, John
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

04/04/2014

04/04/2014

01/01/2013

Resumo

The recent achievement of synthesising a functioning bacterial chromosome marks a coming of age for engineering living organisms. In the future this should allow the construction of novel organisms to help solve the problems facing the human race, including health care, food, energy and environmental protection. In this minireview, the current state of the field is described and the role of synthetic biology in biotechnology in the short and medium term is discussed. It is particularly aimed at the needs of food technologists, nutritionists and other biotechnologists, who might not be aware of the potential significance of synthetic biology to the research and development in their fields. The potential of synthetic biology to produce interesting new polyketide compounds is discussed in detail.

Croatian Science Foundation grant 09/5

German Academic Exchange Service (DAAD)

CNPq-TWAS (Conselho Nacional de Pesquisa do Brazil Third World Academy of Sciences, Brazil)

FAPESP (Fundação de Apoio a Pesquisa do Estado de São Paulo, Brazil)

FAPESP-King’s College

Identificador

Food Technology and Biotechnology, v.51, n.1, p.3-11, 2013

http://www.producao.usp.br/handle/BDPI/44375

http://connection.ebscohost.com/c/articles/87068889/synthetic-biology-novel-approach-construction-industrial-microorganisms

Idioma(s)

eng

Publicador

Faculty of Food Technology and Biotechnology

Chicago

Relação

Food Technology and Biotechnology

Direitos

restrictedAccess

Faculty of Food Technology and Biotechnology

Palavras-Chave #Molecular biotechnology #Industrial microorganisms #DNA synthesis #Homologous recombination #Recombinant gene clusters #Biotecnologia #Microrganismos #DNA #Genes #Recombinação genética
Tipo

article

original article

publishedVersion