Side-chain Modifications of Highly Functionalized 3(2H)-Furanones


Autoria(s): Nardini, Viviani; Rodrigues, Shirley Muniz Machado; Constantino, Mauricio Gomes; Silva, Gil Valdo Jose da
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

21/10/2013

21/10/2013

2012

Resumo

A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives. The isoxazole was prepared by a [3+2] 1,3-dipolar cycloaddition reaction between 3-butyn-2-ol and nitrile oxide.

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)

Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)

Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)

Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)

Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)

Financiadora de Estudos e Projetos (FINEP)

Financiadora de Estudos e Projetos (FINEP)

Identificador

MOLECULES, BASEL, v. 17, n. 10, supl. 1, Part 1, pp. 12151-12162, OCT, 2012

1420-3049

http://www.producao.usp.br/handle/BDPI/35286

10.3390/molecules171012151

http://dx.doi.org/10.3390/molecules171012151

Idioma(s)

eng

Publicador

MDPI AG

BASEL

Relação

MOLECULES

Direitos

openAccess

Copyright MDPI AG

Palavras-Chave #3(2H)-FURANONE #ISOXAZOLE #NATURAL PRODUCTS #SIDE-CHAIN MODIFICATIONS #METABOLITES #CHEMISTRY, ORGANIC
Tipo

article

original article

publishedVersion