Nonlipidized juvenile xanthogranuloma: An unusual variant with a potential diagnostic pitfall
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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| Data(s) |
05/11/2013
05/11/2013
2012
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| Resumo |
Juvenile xanthogranuloma (JXG) is a histiocytic inflammatory disorder that can present different histologic patterns. Classic JXG consists of sheets of foamy histiocytes and numerous multinucleated Touton giant cells. Nonlipidized JXG (NJXG) is one of the unusual variants of JXG, consisting of a diffuse monomorphic infiltrate of mononuclear histiocytes, suggesting an aggressive or malignant tumor due the high mitotic index. However, NJXG behaves clinically as classic JXG. We present an unusual case of a 6-year-old boy who presented an exophytic ulcerated nodule on the lower lip diagnosed as NJXG. The boy is currently well without recurrence three years after surgical excision. (C) 2011 Elsevier Ireland Ltd. All rights reserved. FAPESP (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo) Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) |
| Identificador |
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, CLARE, v. 76, n. 2, supl. 1, Part 1, pp. 295-299, FEB, 2012 0165-5876 http://www.producao.usp.br/handle/BDPI/41730 10.1016/j.ijporl.2011.11.010 |
| Idioma(s) |
eng |
| Publicador |
ELSEVIER IRELAND LTD CLARE |
| Relação |
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY |
| Direitos |
closedAccess Copyright ELSEVIER IRELAND LTD |
| Palavras-Chave | #JUVENILE XANTHOGRANULOMA #NONLIPIDIZED JUVENILE XANTHOGRANULOMA #MITOTIC ACTIVITY #TOUTON CELLS #LIP #IMMUNOHISTOCHEMISTRY #LANGERHANS CELL HISTIOCYTOSES #INCONSPICUOUS FOAM CELLS #GIANT-CELLS #CLINICOPATHOLOGICAL ANALYSIS #ADULT PATIENT #ORAL CAVITY #TUMORS #SKIN #EXPRESSION #DISORDERS #OTORHINOLARYNGOLOGY #PEDIATRICS |
| Tipo |
article original article publishedVersion |
