Biosynthesis of Two Dihydropyrrole-Polyketides from a Marine-Derived Penicillium citrinum
| Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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| Data(s) |
06/11/2013
06/11/2013
2012
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| Resumo |
Feeding experiments with C-13-labeled precursors were performed in order to establish the biosynthesis of two N-acylated dihydropyrroles, (8E)-1-(2,3-dihydro-1H-pyrrol-1-yl)-2- methyldec-8-ene-1,3-dione (1) and 1-(2,3-dihydro-1H-pyrrol-1-yl)-2- methyldecane-1,3-dione (2), isolated from the cultures of a marine-derived Penicillium citrinum. The biosynthesis of both, 1 and 2, involves the incorporation of acetate, methionine and ornithine. Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2009/51199-6, 2010/05100-5] CNPq [142116/2009-2] CNPq |
| Identificador |
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, SAO PAULO, v. 23, n. 10, supl., Part 1, pp. 1783-1788, OCT, 2012 0103-5053 http://www.producao.usp.br/handle/BDPI/42214 10.1590/S0103-50532012005000046 |
| Idioma(s) |
eng |
| Publicador |
SOC BRASILEIRA QUIMICA SAO PAULO |
| Relação |
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY |
| Direitos |
closedAccess Copyright SOC BRASILEIRA QUIMICA |
| Palavras-Chave | #PENICILLIUM CITRINUM #MARINE-DERIVED FUNGUS #MIXED BIOSYNTHESIS #DIHYDROPYRROLE #ANTI-JUVENILE-HORMONE #ASPERGILLUS-NIDULANS #ANTIFUNGAL AGENT #GENE-CLUSTER #PROPIONATE #METABOLITES #TAMBJAMINE #ALKALOIDS #BREVICOMPACTUM #CHEMISTRY, MULTIDISCIPLINARY |
| Tipo |
article original article publishedVersion |
