Glass/PDMS hybrid microfluidic device integrating vertically aligned SWCNTs to ultrasensitive electrochemical determinations


Autoria(s): Moraes, Fernando Cruz; Lima, Renato Sousa; Segato, Thiago Pinotti; Cesarino, Ivana; Cetino, Jhanisus Leonel Melendez; Machado, Sergio Antonio Spinola; Gomez, Frank; Carrilho, Emanuel
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

06/11/2013

06/11/2013

2012

Resumo

This communication reports a promising platform for rapid, simple, direct, and ultrasensitive determination of serotonin. The method is related to integration of vertically aligned single-walled carbon nanotubes (SWCNTs) in electrochemical microfluidic devices. The required microfabrication protocol is simple and fast. In addition, the nanomaterial influenced remarkably the obtained limit-of-detection (LOD) values. Our system achieved a LOD of 0.2 nmol L-1 for serotonin, to the best of our knowledge one of the lowest values reported in the literature.

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2010/08559-9, 2010/11049-2, 2010/11567-3, 2010/038013-4]

Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)

Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) [476523/2009-5]

Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)

Laboratorio Nacional de Nanotecnologia do Centro Nacional de Pesquisa em Energia e Materiais (CNPEM)

Laboratorio Nacional de Nanotecnologia do Centro Nacional de Pesquisa em Energia e Materiais (CNPEM)

Identificador

LAB ON A CHIP, CAMBRIDGE, v. 12, n. 11, supl. 1, Part 3, pp. 1959-1962, JAN, 2012

1473-0197

http://www.producao.usp.br/handle/BDPI/42272

10.1039/c2lc40141j

http://dx.doi.org/10.1039/c2lc40141j

Idioma(s)

eng

Publicador

ROYAL SOC CHEMISTRY

CAMBRIDGE

Relação

LAB ON A CHIP

Direitos

openAccess

Copyright ROYAL SOC CHEMISTRY

Palavras-Chave #CONTACTLESS CONDUCTIVITY DETECTION #GLASSY-CARBON ELECTRODE #CAPILLARY-ELECTROPHORESIS #LIQUID-CHROMATOGRAPHY #ASCORBIC-ACID #NANOTUBE #SEROTONIN #DETECTORS #MICROCHIP #SAMPLES #BIOCHEMICAL RESEARCH METHODS #CHEMISTRY, MULTIDISCIPLINARY #NANOSCIENCE & NANOTECHNOLOGY
Tipo

article

original article

publishedVersion