Gene expression of peripheral blood lymphocytes may discriminate patients with schizophrenia from controls
Contribuinte(s) |
UNIVERSIDADE DE SÃO PAULO |
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Data(s) |
06/11/2013
06/11/2013
2012
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Resumo |
To identify a classifier in schizophrenia, blood gene expression profiling was applied to patients with schizophrenia under different treatments and to controls. Expression of six genes discriminated patients with sensitivity of 89.3% and specificity of 90%, supporting the use of peripheral blood as biological material for diagnosis in schizophrenia. (C) 2012 Elsevier Ireland Ltd. All rights reserved. Fundacao para a Ciencia e Tecnologia/FEDER (Portugal) [POCI/SAU-ESP/58757/2004] GRICES/CAPES International Collaborative Program (Portugal, Brazil) FIPE HCPA |
Identificador |
PSYCHIATRY RESEARCH, CLARE, v. 200, n. 2-3, pp. 1018-1021, DEC 30, 2012 0165-1781 http://www.producao.usp.br/handle/BDPI/42242 10.1016/j.psychres.2012.04.030 |
Idioma(s) |
eng |
Publicador |
ELSEVIER IRELAND LTD CLARE |
Relação |
PSYCHIATRY RESEARCH |
Direitos |
closedAccess Copyright ELSEVIER IRELAND LTD |
Palavras-Chave | #SCHIZOPHRENIA #PERIPHERAL MOLECULAR MARKER #DRUGS #BIPOLAR DISORDER #COMMON VARIANTS #MESSENGER-RNA #ENVIRONMENT #PROFILES #NETWORKS #DYNAMICS #RECEPTOR #SYSTEM #BRAIN #PSYCHIATRY |
Tipo |
article original article publishedVersion |