Gene expression of peripheral blood lymphocytes may discriminate patients with schizophrenia from controls


Autoria(s): Maschietto, Mariana; Silva, Aderbal R.; Puga, Renato D.; Lima, Leandro; Pereira, Carlos B.; Nakano, Eduardo Y.; Mello, Barbara; Gama, Clarissa S.; Belmonte-de-Abreu, Paulo; Carraro, Dirce M.; Palha, Joana A.; Brentani, Helena
Contribuinte(s)

UNIVERSIDADE DE SÃO PAULO

Data(s)

06/11/2013

06/11/2013

2012

Resumo

To identify a classifier in schizophrenia, blood gene expression profiling was applied to patients with schizophrenia under different treatments and to controls. Expression of six genes discriminated patients with sensitivity of 89.3% and specificity of 90%, supporting the use of peripheral blood as biological material for diagnosis in schizophrenia. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

Fundacao para a Ciencia e Tecnologia/FEDER (Portugal) [POCI/SAU-ESP/58757/2004]

GRICES/CAPES International Collaborative Program (Portugal, Brazil)

FIPE HCPA

Identificador

PSYCHIATRY RESEARCH, CLARE, v. 200, n. 2-3, pp. 1018-1021, DEC 30, 2012

0165-1781

http://www.producao.usp.br/handle/BDPI/42242

10.1016/j.psychres.2012.04.030

http://dx.doi.org/10.1016/j.psychres.2012.04.030

Idioma(s)

eng

Publicador

ELSEVIER IRELAND LTD

CLARE

Relação

PSYCHIATRY RESEARCH

Direitos

closedAccess

Copyright ELSEVIER IRELAND LTD

Palavras-Chave #SCHIZOPHRENIA #PERIPHERAL MOLECULAR MARKER #DRUGS #BIPOLAR DISORDER #COMMON VARIANTS #MESSENGER-RNA #ENVIRONMENT #PROFILES #NETWORKS #DYNAMICS #RECEPTOR #SYSTEM #BRAIN #PSYCHIATRY
Tipo

article

original article

publishedVersion